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USPSTF: Do Not Start Low-Dose Aspirin to Prevent CVD in 60+ – Consumer Health News

TUESDAY, April 26, 2022 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends that the choice to provoke low-dose aspirin for major prevention of heart problems (CVD) occasions must be individualized amongst these aged 40 to 59 years and isn’t really useful for these aged 60 years or older. These suggestions kind the premise of a ultimate advice assertion, printed within the April 26 difficulty of the Journal of the American Medical Association.

Janelle M. Guirguis-Blake, M.D., from the Kaiser Permanente Evidence-based Practice Center in Portland, Oregon, and colleagues carried out a scientific assessment of the advantages and harms of aspirin in major prevention of CVD. Data from 11 randomized managed trials (134,470 individuals) and one pilot trial (400 individuals) had been included within the quantitative synthesis. The researchers discovered a major lower in main CVD occasions in affiliation with low-dose aspirin (odds ratio, 0.90). For particular person CVD outcomes, the outcomes had been important, with an analogous magnitude of profit. No important reductions in CVD mortality or all-cause mortality had been noticed. Low-dose aspirin was related to important will increase in complete main bleeding (odds ratio, 1.44) and site-specific bleeding.

Based on these findings, the USPSTF concludes with average certainty that for adults aged 40 to 59 years with a ten p.c or higher 10-year CVD danger, aspirin use for major prevention of CVD occasions has a small internet profit; consequently, the choice to provoke aspirin must be a person one (C advice). For adults aged 60 years or older, initiating aspirin for major prevention of CVD occasions has no internet profit (D advice).

“We want to emphasize that these recommendations are focused on starting aspirin to prevent a first heart attack or stroke,” USPSTF member John Wong, M.D., stated in an announcement.

Evidence Report

Modeling Study

Final Recommendation Statement

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